Genetic code prediction tool FACIL: Fast and Accurate genetic Code Inference and Logo Enter process ID to retrieve a previous search: New run.

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Genetic code prediction tool FACIL infers the genetic code directly from any set of nucleic acid sequences and assigns a Random Forest-based reliability score to its predictions. To run FACIL, start by entering a genome sequence or a set of sequence fragments derived from the same genome into the search box below. It is important that the sequences are derived from the same genome to prevent mixing signals from potentially conflicting genetic codes. For example, a eukaryotic cell may contain up to three different translation codes: nuclear, mitochondrial and plastid. Choose a provisional genetic code to translate your sequences for the initial protein domain search, then hit 'go'. The example DNA sequences are a set of 150 contigs from the Globobulimina pseudospinescens mitochondrial genome (Dutilh et al. Bioinformatics 2011).

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Input sequences (DNA, FASTA format): (example)
Genetic code for provisional translation:	Base1 = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG Base2 = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG Base3 = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG AAs = FFLLSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG 0 User defined 1 The Standard Code 2 The Vertebrate Mitochondrial Code 3 The Yeast Mitochondrial Code 4 The Mold, Protozoan, and Coelenterate Mitochondrial Code and the Mycoplasma/Spiroplasma Code 5 The Invertebrate Mitochondrial Code 6 The Ciliate, Dasycladacean and Hexamita Nuclear Code 9 The Echinoderm and Flatworm Mitochondrial Code 10 The Euplotid Nuclear Code 11 The Bacterial, Archaeal and Plant Plastid Code 12 The Alternative Yeast Nuclear Code 13 The Ascidian Mitochondrial Code 14 The Alternative Flatworm Mitochondrial Code 15 Blepharisma Nuclear Code 16 Chlorophycean Mitochondrial Code 21 Trematode Mitochondrial Code 22 Scenedesmus obliquus mitochondrial Code 23 Thraustochytrium Mitochondrial Code
Reference:	Dutilh, B.E., Jurgelenaite, R., Szklarczyk, R., van Hijum, S.A.F.T., Harhangi, H.R., Schmid, M., de Wild, B., Francoijs, K.-J., Stunnenberg, H.G., Strous, M., Jetten, M.S.M., Op den Camp, H.J.M. and Huynen, M.A. (2011). FACIL: fast and accurate genetic code inference and logo. Bioinformatics 27: 1929-1933. Pubmed, PDF.
Contact:	https://www.radboudumc.nl/en/people/bas-dutilh
Download:	Find the latest stand-alone version of genetic code prediction tool FACIL on SourceForge.

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